Recombinant Human FGF-acidic Protein

Description
Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. 
FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.  FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling.

Full Name
Human Fibroblast Growth Factor acidic

Source
E. coli

Species
Human

Accession #
MN_000800

Molecule Weight
The mature recombinant human FGF acidic consists of 154 amino acids (2-155) and has a predicted molecular mass of 17 kDa.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. The ED50 for this effect is 0.015-0.15 ng/mL in the presence of 10 µg/mL of heparin.

 Storage
-80°C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS