Mutation Surveyor

Description:
Mutation Surveyor® is a powerful DNA sequencing analysis software designed for fast and accurate identification of genetic variants from Sanger sequencing trace files. The software uses patented anti-correlation technology, which physically compares sample sequence traces with reference traces to improve variant detection accuracy.

Mutation Surveyor® supports sequencing files generated by major capillary electrophoresis systems, including Applied Biosystems Genetic Analyzers, Beckman CEQ and Promega Spectrum Compact CE System. The software enables detection of SNPs, homozygous and heterozygous insertions/deletions, and somatic mutations from direct sequencing data.

The software provides automated sequence comparison, reference alignment, variant annotation and reporting tools. Additional features include DNA methylation detection, mitochondrial DNA analysis, allele quantification, Variant Knowledge Database and user management with audit trail functionality.

Features:

• automated Sanger sequencing analysis
• direct DNA variant detection from sequence traces
• patented anti-correlation technology
• SNP detection
• homozygous and heterozygous indel detection
• somatic mutation detection
• reference sequence comparison
• GRCh37 and GRCh38 alignment support
• variant annotation tools
• Variant Knowledge Database
• mitochondrial DNA analysis
• DNA methylation detection
• allele quantification
• customizable reports
• user management with audit trail
• reduced false-positive and false-negative results

Applications:

• Sanger sequencing variant analysis
• SNP analysis
• indel analysis
• heterozygous variant detection
• somatic mutation analysis
• genetic research
• molecular diagnostics
• oncology research
• mitochondrial DNA analysis
• DNA methylation studies
• genetic variant validation
• inherited disease research