Recombinant Human FGF-10 Protein

Description
FGF-10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. 
FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

Full Name
Fibroblast Growth Factor 10

Source
E. coli

Species
Human

Accession #
O15520

Molecule Weight
The mature recombinant human FGF-10 consists of 172 amino acids (37-208) and has a predicted molecular mass of 19.3 kDa.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured in a cell proliferation assay using 4MBr­5 rhesus monkey epithelial cells. The ED50 for this effect is 20-100 ng/mL.

 Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS