Recombinant Human FGF-22 Protein

Description
FGF-22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. 
FGF-22 stimulates the proliferation and activation of cells that express FGF receptor.

Full Name
Fibroblast Growth Factor 22

Source
E. coli

Species
Human

Accession #
Q9HCT0

Molecule Weight
The mature recombinant human FGF-22 consists of 148 amino acids (23-170) and has a predicted molecular mass of 18 kDa.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cells. The ED50 for this effect is 50-300 ng/mL.

Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS