Recombinant Human INF-alpha 4 Protein

Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α4 (interferon α 4) belongs to type 1 interferon family.  IFN-α4 is associated with Rabies, and involved in Toll-like Receptor Signaling Pathway. 

Full Name
Interferon α 4

Source
E. coli

Species
Human

Accession #
X02955

Molecule Weight
The mature recombinant human IFN-α4 is a 19.4 kDa protein.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus (VSV). The ED50 for this effect is typically 2-8 pg/mL.

Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS