Recombinant Human INF-alpha 8 Protein

Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN-α8 (interferon α 8) belongs to type 1 interferon family.  IFN-α8 is induced in peripheral blood mononuclear cells (PBMCs) upon incubation with CpG-oligonucleotides and in plasmacytoid dendritic cells upon incubation with CpG-oligonucleotides or imiquimod.

Full Name
Interferon α 8

Source
E. coli

Species
Human

Accession #
P32881

 Molecule Weight
The mature recombinant human IFN-α8 is a 22 kDa protein (1-189aa).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS