Recombinant Human INF-omega Protein

Description
The interferons (IFN)s are a family of cytokines with potent antiviral, antitumor, and immunomodulatory properties. Interferons are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. Interferons are divided into type I, II, and III. Type I IFNs (IFN-α and IFN-β) are most abundant in number, distribution, and expression.
IFN- ω (interferon omega) a type I interferon, is a monomeric glycoprotein distantly related in structure to IFN-alpha and IFN-beta, but unrelated to IFN-gamma. 

 Full Name
Interferon omega

Source
E. coli

Species
Human

Accession #
X58822

Molecule Weight
The mature recombinant human IFN- ω is a 20 kDa protein (24-195aa).

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/ml, corresponding to a specific activity of >1.0x108 IU/mg.

Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS