Recombinant Human Persephin Protein

Description
Persephin belongs to the GDNF ligand subfamily of the TGF-beta superfamily. It promotes the survival and growth of central dopaminergic and motor neurons, and also is involved in kidney development. But persephin does not support survival of peripheral neurons.

Full Name
Human Persephin protein

Source
E. coli

Species
Human

Accession #
O60542

Molecule Weight
The mature recombinant human Persephin protein consists of 96 amino acids (61-156) and has a predicted molecular mass of 20.5 kDa as a dimer.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured in a cell proliferation assay using TT human medullary thyroid cancer cells. The ED50 for this effect is 4-16 ng/mL.

Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS