Recombinant Human TGF-beta 5 Protein

Description
TGF-beta 5 is a member of the TGF-beta family of growth factors. These proteins are stable, multifunctional factors with a wide variety of effects on the growth and differentiation of virtually all cell types. These actions on growth or differentiation may be stimulatory or inhibitory, depending on the cell type, growth conditions, state of differentiation and on the presence of other growth factors.

Full Name
Transforming growth factor beta 5

Source
E. coli
Species
Human

Accession #
P16176

Molecule Weight
The mature recombinant human TGF-beta 5 consists of 112 amino acids (271-382) and has a predicted molecular mass of 12.6 kDa.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Activity
Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.01-0.03 ng/mL.

Storage
-80 °C, avoid repeated freeze-thaw cycles.

Storage Buffer
PBS