Human Nicotinamide Phosphoribosyltransferase (NAMPT)

Description
Human Nicotinamide Phosphoribosyltransferase (NAMPT) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

Source
E. coli

UniProt ID
P43490

Molecule Weight
The mature recombinant human NAMPT is a 52 kDa protein (1-491aa) with a His-tag at the N-terminus.

Purity
> 95 % as determined by SDS-PAGE

Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method

Storage
-80 Avoid repeated freeze-thaw cycles.