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ApoA1

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APO-100 or APOH-100

ApoA1 (Apolipoprotein  A1) is synthesized in the liver and small intestine, and is the major protein component of high density lipoprotein (HDL) in the plasma. ApoA1 has a unique ability to capture and solubilize free cholesterol, and promotes cholesterol efflux from tissues to the liver for excretion. The process, called reverse cholesterol transport, is thought to inhibit atherogenesis.

Description
ApoA1 (Apolipoprotein  A1) is synthesized in the liver and small intestine, and is the major protein component of high density lipoprotein (HDL) in the plasma. ApoA1 has a unique ability to capture and solubilize free cholesterol, and promotes cholesterol efflux from tissues to the liver for excretion. The process, called reverse cholesterol transport, is thought to inhibit atherogenesis. The recombinant human ApoA1 consists of 244 amino acids and predicts a molecular mass of 28.2 KD.

 

Applications

miRNA in vivo delivery

HDL Assembly

Evaluation of risk for atherosclerotic cardiovascular disease

 

Source: Human

 

Expression System: E. coli


Tag: N-terminal His-tag

 

Purity: >95% as determined by SDS-PAGE

 

Endotoxin Level: Less than 0.1EU/ug by LAL method

 

Recommended Storage Condition: -20°C

 

Expiration date: 12 months

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